|
The Dille–Koppanyi reagent is used as a simple spot-test to presumptively identify barbiturates. It is composed of a mixture of two solutions. Part A is 0.1 g of cobalt(II) acetate dihydrate dissolved in 100 ml of methanol mixed with 0.2 ml of glacial acetic acid. Part B made up of is 5% isopropylamine (v/v) in methanol. Two drops of A are dropped onto the substance followed by one drop of B and any change in colour is observed. The test turns phenobarbital, pentobarbital, amobarbital and secobarbital light purple〔 by complexation of cobalt with the barbiturate nitrogens.〔 〕 The test, in a slightly different formulation, was developed in the 1930s by American pharmacologists Theodore Koppanyi and James M. Dille. ==See also== * Pill testing * Marquis reagent * Froehde's reagent * Zwikker reagent 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dille–Koppanyi reagent」の詳細全文を読む スポンサード リンク
|